Multi-kernel graph embedding for detection, Gleason grading of prostate cancer via MRI/MRS

Multi-kernel graph embedding for detection, Gleason grading of prostate cancer via MRI/MRS

Even though 1 in 6 men in the US, in their lifetime are expected to be diagnosed with prostate cancer (CaP), only 1 in 37 is expected to die on account of it. Consequently, among many men diagnosed with CaP, there has been a recent trend to resort to active surveillance (wait and watch) if diagnosed with a lower Gleason score on biopsy, as opposed to seeking immediate treatment. Some researcher...

Gleason grading of prostate cancer. Contemporary approach.

Automatic Gleason Grading of Prostate Cancer Using Shearlet Transform and Multiple Kernel Learning

Description: The process is a method of classifying prostate tumors as cancerous or benign. It classifies the tumors according to the Gleason grading scale to determine the cancerous nature of the tumor. The process utilizes a shearlet transform, as well as three other features, and combines them via multiple kernel learning. The shearlet transform is used to represent the local structure of im...

Automated Prostate Cancer Diagnosis and Gleason Grading of Tissue Microarrays

We present the results on the development of an automated system for prostate cancer diagnosis and Gleason grading. Images of representative areas of the original Hematoxylin-and-Eosin (H&E)-stained tissue retrieved from each patient, either from a tissue microarray (TMA) core or whole section, were captured and analyzed. The image sets consisted of 367 and 268 color images for the diagnosis an...

Interobserver variability in Gleason histological grading of prostate cancer.

OBJECTIVE The aims of this study were to evaluate the reproducibility of the Gleason grading system and to compare its interobserver variability with the novel Gleason grade grouping proposal using a large sample volume. MATERIALS AND METHODS In total, 407 pathology slides of prostate needle biopsies from 34 consecutive patients with prostate cancer were re-evaluated. The International Societ...